When the mouse is malfunctioning, it will often disappear for short and long periods of time. To resolve this issue, you'll have to try a few different solutions since there may be more than one issue affecting your disappearing mouse. Following are the steps given to resolve such issue.
1). Clean the bottom of your laser lens mouse with a damp cloth. Dirt can build up on the lens and block the light that transmits to the mouse. If you have a mouse with a ball, turn the outer casing of the ball's compartment counter-clockwise, carefully remove the ball and clean it with a damp cloth. Dry the laser lens or ball with a paper towel.
2). Plug your USB mouse into another USB port on your computer. Sometimes USB ports can stop working.
